Professor

Federica Vacondio graduated in Pharmaceutical Chemistry and Technology from the University of Parma in 1998 and obtained her PhD in Pharmaceutical Chemistry and Technology from the University of Pavia in 2002. She has conducted research in Italy at the Institute of Molecular Sciences and Technologies (CNR-ISTM) in Padua (2004) and abroad at the Faculté des Sciences of the Université de Lausanne (UNIL), Switzerland in 2001 and the Gillespie Neuroscience Research Facility, University of California Irvine (UCI), USA (2007). After serving as a
researcher at the Faculty of Pharmacy of the University of Parma in 2001, she has been an Associate Professor affiliated with SSD CHEM-07/A (Pharmaceutical Chemistry) at the Department of Food and Drug Sciences of the same university since 2014. Prof. Vacondio is involved in the application of analytical methods based on tandem and high-resolution mass spectrometry to the characterization of drug metabolism and the study of modulations of the lipidome and cellular metabolome in response to a pathological state or drug treatment.
Prof. Vacondio is an expert in in vitro analysis of chemical-physical properties and ADME with the aim of analyzing the relationships between structure and properties (SPR) and optimizing the pharmacokinetics of drugs. Her research activity covers several areas: (i) central and peripheral signaling mediated by endocannabinoids and fatty acid ethanolamides, with particular attention to the effects of inhibitors and modulators of the degradative enzymes Fatty Acid Amide Hydrolase (FAAH), Monoglyceridelipase (MGL), and N-acylethanolamine acid amidase (NAAA) as potential
neuroprotective, anti-inflammatory, and analgesic agents; (ii) the mechanisms of metabolic reprogramming and cellular resistance to treatment with tyrosine kinase inhibitors in non-small cell lung cancer; (iii) the cross-talk between drugs and the gut microbiota.