Researcher at Lab. Experimental Neurophysiology by Dr. Picconi Barbara

Dr. Valeria Calabrese carried out her research activity from 2016 to 2018 at the Neurophysiology Laboratory directed by Professor Paolo Calabresi, Santa Lucia Foundation, IRCCS, Rome, from 2019 to today at the Laboratory of Neurophysiology directed by Dr. Barbara Picconi. During these research experiences, he participated directly in several projects related to the study of changes in synaptic plasticity (long-term potentiation, depression long-term and depowering of spiny projection neurons) in an animal model of Parkinson's disease induced by stereotactic injection of 6-OHDA into the medial bundle of the forebrain and dyskinetic induced by a treatment chronic with Levodopa. She specializes in using the technique of intracellular recordings in brain areas such as dorso-striatal striatum, the CA1 hippocampus and CA3 dentate gyrus, and amperometrics in parkinsonian mouse models. From 2018 to 2021 he completed his PhD with scholarship at the University of Perugia in “Clinical and molecular medicine”, with the release of the final project “Rapamycin, by Inhibiting mTORC1 Signaling, Prevent the Loss of Striatal Bidirectional Synaptic Plasticity in a Rat Model of L-DOPA-Induced”. In 2019, thanks to the FENS scholarship for “CAJAL course on Advanced Techniques for Synapse Biology” at Bourdeax University, France, has deepened his knowledge on electrophysiology and microscopy in cell cultures from hippocampus of mice.
In 2019, thanks to the EMBO scholarship with the project “Alpha-synuclein effects on neurons transdifferentiated from fibroblasts extracted from patients with Parkinson's Disease: voltammetric, electrophysiologic and morphological analyses” at dr. Massimiliano Caiazzo's laboratory at the University of Utrecht, the Netherlands, deepened his knowledge regarding the characterization of personalized therapies starting from the fibroblasts of Parkinsonian patients. Since 2024, the dr. Calabrese serves as a Fixed-Term Researcher (RTT) at the San Raffaele Telematic University, Rome in the scientific disciplinary sector BIO/09 Physiology, continuing his constant research interest towards i
mechanisms that regulate human behavior. Prof Valeria Calabrese is the author of 14 articles published in international journals Official H Index Scopus
Articles 14
Quotes 482
H-index 8