11.2022 - 02.2026

Study of neural correlates of inhibition mechanisms induced by magnetic stimulation trilobite

Studies carried out in patients with corpus callosum dysfunction showed that the ipsilateral silent period is a measure of interhemispheric inhibition, that is, a measure of the inhibitory activity that one hemisphere exerts on the contralateral one. This parameter is widely studied using the surface electromyography technique. However, it is generated at the cortical level following magnetic stimulation. There are to date no studies inherent to the changes in contralateral hemisphere activity associated with the phenomenon of the ipsilateral silent period.

Project objective
To study cortical activity associated with the ipsilateral silent period in the hemisphere contralateral to the hemisphere stimulated by transcranial magnetic stimulation.

• Basic neuroscience: study of the mechanisms of interhemispheric interaction in humans.
• Neurorehabilitation: tool for monitoring and evaluating the effects on the activity of motor circuits at the cortical level of therapeutic interventions in neurological patients.
• Clinical neurology: identification of new functional biomarkers and study of cortical connectivity in neurodegenerative white matter pathologies, such as multiple sclerosis. 

Settori Scientifico Disciplinari

BIO/09  PHYSIOLOGY

Spoke 4 : Perception and Brain-Body Interaction

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