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Mnesys - Project Lines

 

PNRR Line:
Mnesys an integrated multiscale approach to the study of the nervous system in health and disease

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Mnesys an integrated multiscale approach to the study of the nervous system in health and disease

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Generation Echo project

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Generation Echo project

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2-BRAINED (2-Brain Regulation to Achieve Improved Neuroprotection during Early Development)

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2-BRAINED (2-Brain Regulation to Achieve Improved Neuroprotection during Early Development)

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ARIEL (Autonomic Regulation through Interactions in Early Life)

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ARIEL (Autonomic Regulation through Interactions in Early Life)

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STROKEMARK C

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STROKEMARK C

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Macro2Micro - Novel implantable neuroelectronic devices for identification of biomarkers of epileptogenic activity using high-resolution microelectrode arrays

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Macro2Micro - Novel implantable neuroelectronic devices for identification of biomarkers of epileptogenic activity using high-resolution microelectrode arrays

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Develop in vitro models of rare and more prevalent neurodegenerative diseases using iPSC-derived 2 D and 3 D cell cultures of patients.

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Develop in vitro models of rare and more prevalent neurodegenerative diseases using iPSC-derived 2 D and 3 D cell cultures of patients.

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Neurodegeneration, trauma and stroke – MNESYS

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Neurodegeneration, trauma and stroke – MNESYS

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Early Identification of Neonatal Cerebral Damage: Study of Neurological Biomarkers and Functional Measures

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Early Identification of Neonatal Cerebral Damage: Study of Neurological Biomarkers and Functional Measures

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FULL-MINDSET: FULLy iMmersive vIrtual reality-based cogNitive training in schizophrenia and bipolar Disorder: a single blind randomized controlled trial in a real-world SETting

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FULL-MINDSET: FULLy iMmersive vIrtual reality-based cogNitive training in schizophrenia and bipolar Disorder: a single blind randomized controlled trial in a real-world SETting

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Common and rare genetic variants and clinical variables associated to the risk of antipsychotic-induced extrapyramidal symptoms or weight gain in persons with schizophrenia or bipolar disorder - VARASE

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Common and rare genetic variants and clinical variables associated to the risk of antipsychotic-induced extrapyramidal symptoms or weight gain in persons with schizophrenia or bipolar disorder - VARASE

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Advanced brain imaging for mood and psychotic disorders

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Advanced brain imaging for mood and psychotic disorders

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Pharmacology for precision medicine in psychotic mood disorders

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Pharmacology for precision medicine in psychotic mood disorders

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Project Study of the neurocognitive mechanisms underlying sign-tracker and goal-tracker behavioral phenotypes in a associative learning model for appetitive stimuli

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Project Study of the neurocognitive mechanisms underlying sign-tracker and goal-tracker behavioral phenotypes in a associative learning model for appetitive stimuli

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Optimization of cellular models for the development of innovative therapies for diseases neurodegenerative, inflammatory/demyelinating and rare with a predominantly neurological phenotype B

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Optimization of cellular models for the development of innovative therapies for diseases neurodegenerative, inflammatory/demyelinating and rare with a predominantly neurological phenotype B

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Optimization of animal models for the development of innovative therapies for neurodegenrative, inflammatory/demyelinating and rare diseases with a predominantly neurological phenotype C

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Optimization of animal models for the development of innovative therapies for neurodegenrative, inflammatory/demyelinating and rare diseases with a predominantly neurological phenotype C

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Preclinical models for the physiopathological transition

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Preclinical models for the physiopathological transition

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Cognitive plasticity in fish models

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Cognitive plasticity in fish models

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Neural mechanisms of primate sensorimotor integration during virtual reality prehension and navigation actions

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Neural mechanisms of primate sensorimotor integration during virtual reality prehension and navigation actions

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Optical flows and virtual reality: how the brain interprets movement.

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Optical flows and virtual reality: how the brain interprets movement.

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Information and structure from neural code through the lens of new analysis techniques

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Information and structure from neural code through the lens of new analysis techniques

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Modeling brain oscillations, connectivity, and network alterations

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Modeling brain oscillations, connectivity, and network alterations

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Oxytocin induces the formation of distinctive cortical representations and cognitions biased toward familiar mice

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Oxytocin induces the formation of distinctive cortical representations and cognitions biased toward familiar mice

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Characterization of intra- and inter-individual differences in bodily self-awareness

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Characterization of intra- and inter-individual differences in bodily self-awareness

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Characterization of the interaction between internal and external signals in constructing bodily self awareness

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Characterization of the interaction between internal and external signals in constructing bodily self awareness

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Creating an innovative database of “emotional walk" videos for neuroscience

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Creating an innovative database of “emotional walk" videos for neuroscience

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Study of the impact of emotions on temporal prediction

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Study of the impact of emotions on temporal prediction

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Prediction of the priming effect of the atmosphere via neurophysiological correlates and features individual

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Prediction of the priming effect of the atmosphere via neurophysiological correlates and features individual

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Study of neural correlates of inhibition mechanisms induced by magnetic stimulation trilobite

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Study of neural correlates of inhibition mechanisms induced by magnetic stimulation trilobite

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Definition of a new protocol for evaluating the positional sense of moving limbs

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Definition of a new protocol for evaluating the positional sense of moving limbs

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Autonomic control and brain-body regulation

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Autonomic control and brain-body regulation

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Developing an EEG-EMG environment for investigating cortical representation of upper-limb movement

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Developing an EEG-EMG environment for investigating cortical representation of upper-limb movement

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A multiscale integrated approach to the study of the nervous system in health and disease

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A multiscale integrated approach to the study of the nervous system in health and disease

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Validazione di modelli sinaptici semplificati tridimensionali per lo studio delle relazioni tra sistema immunitario e nervoso in condizioni fisiopatologiche

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Validazione di modelli sinaptici semplificati tridimensionali per lo studio delle relazioni tra sistema immunitario e nervoso in condizioni fisiopatologiche

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A multiscale integrated approach to the study of the nervous system in health and disease

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A multiscale integrated approach to the study of the nervous system in health and disease

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PREDAMUS – PREDiction of lithium response using Algorythms based on MUltimodal Signatures

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PREDAMUS – PREDiction of lithium response using Algorythms based on MUltimodal Signatures

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Ricerca di varianti genetiche come fattori di rischio per i disturbi dell’umore e psicotici

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Ricerca di varianti genetiche come fattori di rischio per i disturbi dell’umore e psicotici

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_GEEKS- Evaluation of Gene- Environment interaction and protective Effects of Ketamine in Shank2 and Shank3 mice

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_GEEKS- Evaluation of Gene- Environment interaction and protective Effects of Ketamine in Shank2 and Shank3 mice

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“ConVestDev” - Atlas of structural and functional connectivity of the vestibular network in human neonates and infants

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“ConVestDev” - Atlas of structural and functional connectivity of the vestibular network in human neonates and infants

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Epigenetic and biological mechanisms of individual vulnerability to social-stress related neuropsychiatric and cardiovascular disorders

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Epigenetic and biological mechanisms of individual vulnerability to social-stress related neuropsychiatric and cardiovascular disorders

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Architecture and dynamics of the social brain in the monkey

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Architecture and dynamics of the social brain in the monkey

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Plastic potentials of the social brain

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Plastic potentials of the social brain

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Identificazione e caratterizzazione di meccanismi molecolari responsabili della neurodegenerazione in modelli di ischemia cerebrale

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Identificazione e caratterizzazione di meccanismi molecolari responsabili della neurodegenerazione in modelli di ischemia cerebrale

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Validazione di modelli sperimentali di ischemia cerebrale

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Validazione di modelli sperimentali di ischemia cerebrale

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Fenotipizzazione clinica, prognosi e predittori di outcome in pazienti adolescenti e adulti con disturbi psicotici o affettivi

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Fenotipizzazione clinica, prognosi e predittori di outcome in pazienti adolescenti e adulti con disturbi psicotici o affettivi

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Integrated technologies for brain connectomics

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Integrated technologies for brain connectomics

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Sviluppo di strategie innovative di NDDS (nano-drug delivery system)

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Sviluppo di strategie innovative di NDDS (nano-drug delivery system)

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Dalle lesioni ischemiche alla riparazione cerebrale: verso nuove terapie elettroceutiche nei modelli animali (From ischemic lesions to brain repair: advancing electroceutical therapies in animal models)

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Dalle lesioni ischemiche alla riparazione cerebrale: verso nuove terapie elettroceutiche nei modelli animali (From ischemic lesions to brain repair: advancing electroceutical therapies in animal models)

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Neural plasticity and functional brain connectivity in applied neurophysiopathology

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Neural plasticity and functional brain connectivity in applied neurophysiopathology

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Advancing fNIRS integration with f/MRI for brain connectomics in healthy and diseased brains

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Advancing fNIRS integration with f/MRI for brain connectomics in healthy and diseased brains

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Neural dynamics and plasticity: Exploring the potential of explainable AI methods to study neuronal dynamics, connectivity, and plasticity for neurorehabilitation

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Neural dynamics and plasticity: Exploring the potential of explainable AI methods to study neuronal dynamics, connectivity, and plasticity for neurorehabilitation

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3T-MRI and neurophysiological methods to explore structural and functional brain networks (i.e. vision and sensory-motor) connectivity changes induced by neurostimulation, brain damage and rehabilitation

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3T-MRI and neurophysiological methods to explore structural and functional brain networks (i.e. vision and sensory-motor) connectivity changes induced by neurostimulation, brain damage and rehabilitation

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Modelli interpretabili di connettività cerebrale per la medicina personalizzata

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Modelli interpretabili di connettività cerebrale per la medicina personalizzata

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Dinamiche neurali e plasticità nella neuroriabilitazione

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Dinamiche neurali e plasticità nella neuroriabilitazione

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Developing innovative anti-inflammatory agents and drug delivery strategies to fight neuroinflammation

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Developing innovative anti-inflammatory agents and drug delivery strategies to fight neuroinflammation

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Gut microbiota in neuropsychiatric disorders

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Gut microbiota in neuropsychiatric disorders

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Progettazione, sintesi, caratterizzazione e formulazione di ligandi innovativi del TSPO come regolatori della risposta infiammatoria microgliale per uso terapeutico nelle demenze

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Progettazione, sintesi, caratterizzazione e formulazione di ligandi innovativi del TSPO come regolatori della risposta infiammatoria microgliale per uso terapeutico nelle demenze

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Caratterizzazione di un modello tossicologico murino di SLA mediante esposizione alla tossina L BMAA

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Caratterizzazione di un modello tossicologico murino di SLA mediante esposizione alla tossina L BMAA

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Drug discovery, development and delivery for mood and psychotic disorders (Identificazione, sviluppo e applicazioni di farmaci innovativi per i disturbi dell’umore e psicotici)

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Drug discovery, development and delivery for mood and psychotic disorders (Identificazione, sviluppo e applicazioni di farmaci innovativi per i disturbi dell’umore e psicotici)

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Neuronal homeostasis and brain-environment interaction - Organelle homeostasis in brain pathophysiology and innovative molecular interventions to correct organelle dysfunction.

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Neuronal homeostasis and brain-environment interaction - Organelle homeostasis in brain pathophysiology and innovative molecular interventions to correct organelle dysfunction.

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Plasticità e riorganizzazione cerebrale correlate al tumore

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Plasticità e riorganizzazione cerebrale correlate al tumore

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L’impatto del cross-talk Microbiota-Immunità nella NeuroInfiammazione

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L’impatto del cross-talk Microbiota-Immunità nella NeuroInfiammazione

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WP1 Anatomo-functional mechanisms of neurodevelopment and social cognition

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WP1 Anatomo-functional mechanisms of neurodevelopment and social cognition

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Dinamiche neurali dell’esperienza cosciente in condizioni fisiologiche e patologiche

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Dinamiche neurali dell’esperienza cosciente in condizioni fisiologiche e patologiche

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Ruolo della via dorsale nella percezione e nell’integrazione sensorimotoria

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Ruolo della via dorsale nella percezione e nell’integrazione sensorimotoria

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Studio dei meccanismi molecolari e comportamentali indotti dallo stress precoce nel cervelletto in modelli murini.

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Studio dei meccanismi molecolari e comportamentali indotti dallo stress precoce nel cervelletto in modelli murini.

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Studio del recettore FPR2 nella progressione e nella metastasi del glioblastoma

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Studio del recettore FPR2 nella progressione e nella metastasi del glioblastoma

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Modelli 2D e 3D derivati da cellule staminali di tumori cerebrali

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Modelli 2D e 3D derivati da cellule staminali di tumori cerebrali

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Disbiosi precoce e neurosviluppo: microbiota, epigenetica e asse intestino-cervello

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Disbiosi precoce e neurosviluppo: microbiota, epigenetica e asse intestino-cervello

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Innovative 2D and 3D platforms for genotype/phenotype correlation and preclinical drug studies in neuromuscular and brain diseases

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Innovative 2D and 3D platforms for genotype/phenotype correlation and preclinical drug studies in neuromuscular and brain diseases

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Sviluppo di modelli in vitro della barriera ematoencefalica per lo studio del ruolo di canali ionici

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Sviluppo di modelli in vitro della barriera ematoencefalica per lo studio del ruolo di canali ionici

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Network neuro-ossidativo nella regolazione della funzione di barriera intestinale

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Network neuro-ossidativo nella regolazione della funzione di barriera intestinale

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Drug repurposing come approccio innovativo per nuove indicazioni terapeutiche in neurooncologia

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Drug repurposing come approccio innovativo per nuove indicazioni terapeutiche in neurooncologia

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Modulazione del microbiota intestinale: approcci terapeutici per la tutela dell’omeostasi intestinale

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Modulazione del microbiota intestinale: approcci terapeutici per la tutela dell’omeostasi intestinale

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Microbiota intestinale e Parkinson: sviluppo di modelli sperimentali per migliorare efficacia e sicurezza terapeutica

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Microbiota intestinale e Parkinson: sviluppo di modelli sperimentali per migliorare efficacia e sicurezza terapeutica

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DESIGN AND STRUCTURAL INVESTIGATIONS OF PEPTIDE ANT METAL COMPLEXES-BASED THERAPEUTICS IN NEURODEGENERATIVE DISEASES

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DESIGN AND STRUCTURAL INVESTIGATIONS OF PEPTIDE ANT METAL COMPLEXES-BASED THERAPEUTICS IN NEURODEGENERATIVE DISEASES

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Neuroinfiammazione, canali ionici e plasticità omeostatica: meccanismi di protezione e adattamento neuronale

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Neuroinfiammazione, canali ionici e plasticità omeostatica: meccanismi di protezione e adattamento neuronale

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Validation of VEGFR-1 targeting in patient derived glioblastoma experimental models

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Validation of VEGFR-1 targeting in patient derived glioblastoma experimental models

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Innovative cellular models for mood and psychotic disorders

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Innovative cellular models for mood and psychotic disorders

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