Funding: The EU-GEI Study is funded by the European Community's Seventh Framework Programme [HEALTH-F2-2010-241909] (Project EU-GEI) and the São Paulo Research Foundation [2012/0417-0]. Monica Aas is supported by a Medical Research Council (MRC) fellowship [MR/W027720/1]. Luis Alameda was supported by fellowships from Fondation Adrian et Simone Frutiger and Carigest SA. Celso Arango has received support from the Spanish Ministry of Science, Innovation and Universities, Instituto de Salud Carlos III (ISCIII), co-financed by the European Union, European Regional Development Funds from the European Commission, ‘A way of making Europe’, financed by the European Union NextGenerationEU [PMP21/00051, PI19/01024, PI22/01824], CIBERSAM, Government of the Community of Madrid [B2017/BMD-3740, AGES-CM-2], European Union Structural Funds, European Union Seventh Framework Programme, European Union H2020 Programme under the Innovative Medicines Initiative 2 Joint Undertaking: Project PRISM-2 [101034377], Project AIMS-2-TRIALS [777394], Horizon Europe, the National Institute of Mental Health [1U01MH124639-01 ProNET, 5P50MH115846-03 FEP-CAUSAL], Fundación Familia Alonso and Fundación Alicia Koplowitz. Helen L. Fisher, Charlotte Gayer-Anderson and Craig Morgan are supported by the Economic and Social Research Council (ESRC) Centre for Society and Mental Health at King's College London [ES/S012567/1]. Diego Quattrone is supported by the MRC Clinical Academic Research Partnership [MR/W030608/1]. Edoardo Spinazzola was supported by Lord Leverhulme's Charitable Trust and the Velvet Foundation and by the MRC [MR/T007818/1]. Bart P. Rutten is funded by a VIDI award from the Dutch Research Council [91.718.336]. The views expressed are those of the authors and not necessarily those of the ESRC or King's College London.